Indian researchers have identified common metabolites linked to pancreatic and glioma cancers, which could lead to improved early diagnosis and more effective treatments for these diseases. The findings were reported by IANS, a partner of TV BRICS.
The study examined metabolites found in exosomes – nano-sized vesicles carrying tumour-derived compounds – from pancreatic, lung, and glioma cancer cell lines. These biomarkers offer a potential non-invasive method for early detection, addressing a crucial need for diagnosing aggressive cancers that are often detected at advanced stages.
The research team used a multi-technique approach, incorporating Nanoparticle Tracking Analysis (NTA), Electron Microscopy (EM), Western Blot (WB), Fourier Transformed Infrared Spectroscopy (FTIR), untargeted Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS), and Nuclear Magnetic Resonance (NMR). According to the report, this comprehensive methodology provides a more precise characterisation of exosomes than conventional single-method studies.
Experts suggest this discovery could significantly improve treatment efficacy, particularly through personalised therapies designed to interfere with dysregulated metabolic pathways in cancer cells. Such targeted interventions could reduce side effects and improve patient outcomes, representing a significant advance in cancer diagnostics and therapeutics, the source claims.
